Histamine release and its inhibition by antihistamines
نویسندگان
چکیده
منابع مشابه
Histamine, histamine receptors and antihistamines: new concepts.
Drugs with antihistamine action are the most commonly prescribed medication in daily dermatologic practice, both to adults and children. This article addresses new concepts of the role of histamine receptors (H1 receptors) and discusses the anti-inflammatory effects of these drugs. Second generation antihistamines differs from first generation because of their high specificity and affinity for ...
متن کاملHistamine release inhibition in anti-inflammatory mechanism.
Rats were depleted of skin histamine by more than 80 % by intraperitoneal injections of sinomenine with daily increasing doses for 6 days. In these rats, egg-white edema induced in the hind paws was inhibited by 68 % of control. The weight of the wall of granuloma pouch made by croton oil was also evidently smaller in the rat treated similarly with sinomenine than that of control. This suggests...
متن کاملCentral effect of histamine and antihistamines on food intake in freely feeding and food-deprived rabbits
Several lines of evidence suggest that brain histamine may be involved in the central control of food intake. The effect of histamine on feeding is mediated through three kinds of receptors (H1, H2, and H3). The present study was designed to investigate the effect of intracerebroventricular injection of histamine, promethazine (H1 antagonist) and ranitidine (H2 antagonist) on food intake of fre...
متن کاملCentral effect of histamine and antihistamines on food intake in freely feeding and food-deprived rabbits
Several lines of evidence suggest that brain histamine may be involved in the central control of food intake. The effect of histamine on feeding is mediated through three kinds of receptors (H1, H2, and H3). The present study was designed to investigate the effect of intracerebroventricular injection of histamine, promethazine (H1 antagonist) and ranitidine (H2 antagonist) on food intake of fre...
متن کاملHistamine and its Releasing Agents
Spontaneous histamine release from isolarted Mastcells was found to be independent of calcium in the concentration range up to 1 m. mole/lit. Phosphatidyl serine do not change the effect of calcium on spontaneous release. The activation of anaphyla.ctic histamine release by calcium is potentiated by phosphatidyl serine but the laitter can't do so w1th strontium. Mastcells, pretreated with AT...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1957
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.53.1029